The museum contains collections of prehistoric and archaic findings from excavations of the British School in Emborios, Neolithic findings of the British excavations in Aghio Galas, Archaic and Classical findings from the British excavations in Fana and various findings from the salvage excavations conducted by the 20th Ephorate of Byzantine Antiquities. Renovation was completed in 1998 and the museum was open to the public in November 1999.

The museum of Chios was constructed between 1966 and 1971 in an area of 2500 sq meters. The building is comprised of exhibition rooms, storerooms, workshops and offices which cover an area of 1200 sq. meters.

The Byzantine Museum in Chios is contained within the 19th Century Ottoman mosque which is located in the central town square. This museum has been in operation since 1980 and contains items that were donated from collections as well as findings discovered in local excavations. The dates of the items on display range from the Early Christian period to the post-Byzantine period (5th – 18th century).

The museum is comprised of a timber-roofed porch, a large basement and a main room. Currently, the mosque porch and the courtyard are only open to the public. The remaining portion is still under renovation.

The courtyard displays stone objects discovered during excavations as well as tombstones from Muslim and Jewish graves. There is a significant collection of sculptures dated during the Genoese occupation of Chios between 1345-1566 which serves as evidence of the period. Worthwhile items included in this collection are the sarcophagus of Ottuboni Ioustiniani located in the courtyard next to the stairway as well as two large slabs from lintels with carvings of Aghios Georghios (St. George) slaying a dragon displayed on the porch. At least one item was brought from Genoa.

On the right side of the courtyard, canons made from iron and brass are on display. They were taken from the bastions of the Castle (Fortress) of Chios whilst it has been determined that two of the canons were constructed in 1687 and 1689, respectively. A third canon is from France since it has the coat of arms of the kings of France inscribed.

Also contained in the porch are column capitals of the 6th century AD, an iconostasis closure slab, impost blocks of double half-columns with crosses and other objects that belong to the various churches of Chios. The wall-paintings that were detached from the Byzantine church of Panaghia Krina (dated late 12th century) are also on display. The painter Michael Chomatzas executed in 1734 these wall paintings.

The Chios’ Maritime Museum is the realization of a dream by its founders – all being among those who make up the Maritime wonder of Chios. It was their wish to establish a residence – museum in one of the largest shipping centers, the island of Chios, which would represent the contemporary Greek maritime spirit.

The Chios’ Maritime Museum is located in the center of the city, housed in a mansion belonging to the late Anastassios and Marouko Pateras. The house was donated in 1991 by the inheritors of the estate to a public benefit foundation, which bears their name.

In 1995 the Chairman, John Kolliaros and the members of "Friends of Folklore Museum of Kalimasia" corporation began to gather folklore material. They thought to use the basement of the junior high school, which was a total surface of 550 m2.

Initially with the aid of worthy fellow villagers they erected the oil-press and the ouzo distillery. Next they constructed traditionally with stone the blacksmith's, the tailor's shop, the shoemaker's shop, the traditional house, the coffee-grocer's and they made places for job of the barber, mattress maker, candle maker, basket maker, butcher etc.

The need to protect, but also to teach the youth and the visitors led the citizens of Kourounia and particularly the church committee to establish the Kourounia Ecclesiastical Museum. This is the first purely Ecclesiastical Museum on the island of Chios. The Museum is housed in the village’s Old Primary School (1913), which was restored for this reason and is divided into four sections:

The first section presents paintings by the great byzantine hagiographer Georgios Panagiotakis, who lived in Chios at the beginning of the past century.

The second section presents photographic material of religious manners and customs of Kourounia citizens. Effort are being made to complete two more sections that concern ecclesiastical utensils and books, although some of these are already being displayed in the ecclesiastical museum.

The municipality of Kambochora in its many cultural endeavors established and opened its Folklore Museum in the residential area of Chalkios. The museum which operates under the supervision of the Cultural and New Generation organization of the municipality, exhibits traditional objects from the regional heritage in complete harmony with the daily habits of the simple residents of the region.

The municipality of Kambochora having the delight and magnificence of the cultural heritage of Kambochora for years now have contributed in promoting the cultural spirit through a series of actions and activities. Along these lines the municipality has organized an expedition of collecting traditional folklore objects establishing the Folklore Museum in Chalkios. The restored area of the oil press has become a museum which can be visited by every lover of local history.